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  "Package": "AdaptiveTrialsR",
  "Title": "Bayesian and Adaptive Clinical Trial Simulation and Monitoring",
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  "Authors@R": "person(\"Muhammad Zahir\", \"Khan\", email = \"zahirstat007@gmail.com\", role = c(\"aut\", \"cre\"))",
  "Description": "Provides tools for simulating and evaluating Bayesian and\nadaptive clinical trial designs with binary outcomes. The\npackage includes methods for trial simulation, posterior and\npredictive probability monitoring, adaptive randomisation,\nBayesian treatment effect estimation, dose-finding, Simon\ntwo-stage phase II designs, group sequential monitoring\nboundaries, operating characteristic evaluation, and interim\ndecision support. The implementation is motivated by\nestablished Bayesian and adaptive design methodology, including\nSimon's two-stage design for phase II trials Simon (1989)\n<doi:10.1016/0197-2456(89)90015-9>, Bayesian adaptive clinical\ntrial approaches described by Berry et al. (2010,\nISBN:9781439825488), and modern adaptive trial frameworks\nreviewed by Pallmann et al. (2018)\n<doi:10.1186/s12916-018-1017-7>.",
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    "decision_summary",
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      "title": "Adaptive Randomisation Probabilities",
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      "page": "analyse_trial_data",
      "title": "Analyse Real Trial Data Using Bayesian Monitoring",
      "topics": [
        "analyse_trial_data"
      ]
    },
    {
      "page": "compare_trial_scenarios",
      "title": "Compare Operating Characteristics Across Trial Scenarios",
      "topics": [
        "compare_trial_scenarios"
      ]
    },
    {
      "page": "create_trial_template",
      "title": "Create a Trial Data Template",
      "topics": [
        "create_trial_template"
      ]
    },
    {
      "page": "crm_dose_finding",
      "title": "Simple Bayesian CRM Dose-Finding Summary",
      "topics": [
        "crm_dose_finding"
      ]
    },
    {
      "page": "decision_summary",
      "title": "Summarise Final Decisions from Adaptive Trial Simulations",
      "topics": [
        "decision_summary"
      ]
    },
    {
      "page": "estimate_treatment_effect",
      "title": "Estimate Bayesian Treatment Effect for Binary Trial Outcomes",
      "topics": [
        "estimate_treatment_effect"
      ]
    },
    {
      "page": "export_figures_to_desktop",
      "title": "Export Package Figures Folder to Desktop",
      "topics": [
        "export_figures_to_desktop"
      ]
    },
    {
      "page": "export_trial_results",
      "title": "Export Adaptive Trial Simulation Results",
      "topics": [
        "export_trial_results"
      ]
    },
    {
      "page": "group_sequential_boundary",
      "title": "Group Sequential Monitoring Boundaries",
      "topics": [
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    {
      "page": "interim_monitoring",
      "title": "Bayesian Interim Monitoring for Adaptive Clinical Trials",
      "topics": [
        "interim_monitoring"
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    },
    {
      "page": "plot_dose_finding",
      "title": "Plot Bayesian Dose-Finding Results",
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      "title": "Plot Group Sequential Monitoring Boundaries",
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      "title": "Plot Operating Characteristics from Simulated Adaptive Trials",
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    {
      "page": "plot_posterior_density",
      "title": "Plot Posterior Density for Trial Arms",
      "topics": [
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    },
    {
      "page": "plot_posterior_intervals",
      "title": "Plot Posterior Credible Intervals for Trial Arms",
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      "title": "Plot Sample Size Distribution from Adaptive Trial Simulations",
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      "title": "Plot Bayesian Treatment Effect",
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