Package: AdaptiveTrialsR Title: Bayesian and Adaptive Clinical Trial Simulation and Monitoring Version: 0.1.0 Authors@R: person("Muhammad Zahir", "Khan", email = "zahirstat007@gmail.com", role = c("aut", "cre")) Description: Provides tools for simulating and evaluating Bayesian and adaptive clinical trial designs with binary outcomes. The package includes methods for trial simulation, posterior and predictive probability monitoring, adaptive randomisation, Bayesian treatment effect estimation, dose-finding, Simon two-stage phase II designs, group sequential monitoring boundaries, operating characteristic evaluation, and interim decision support. The implementation is motivated by established Bayesian and adaptive design methodology, including Simon's two-stage design for phase II trials Simon (1989) , Bayesian adaptive clinical trial approaches described by Berry et al. (2010, ISBN:9781439825488), and modern adaptive trial frameworks reviewed by Pallmann et al. (2018) . License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Imports: stats, utils, dplyr, ggplot2, rlang Suggests: testthat (>= 3.0.0) URL: https://github.com/zerish12/AdaptiveTrialsR BugReports: https://github.com/zerish12/AdaptiveTrialsR/issues Config/testthat/edition: 3 Repository: https://zerish12.r-universe.dev Date/Publication: 2026-06-10 23:39:11 UTC RemoteUrl: https://github.com/zerish12/adaptivetrialsr RemoteRef: HEAD RemoteSha: 4febd4b79e8ad3391d7fa342cb616b125d86723b NeedsCompilation: no Packaged: 2026-10-15 09:05:06 UTC; root Author: Muhammad Zahir Khan [aut, cre] Maintainer: Muhammad Zahir Khan